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R65.2 - Severe sepsis


The ICD 10 Code for Severe sepsis is listed as R65.2.
Additional information concerning this code and description can be found below including ICD 9 crosswalks / GEMS, chapter information, and DRGs where available.

ICD 10 CM Field Value
Diagnosis Code: R65.2
Description: Severe sepsis
  • Infection with associated acute organ dysfunction
  • Sepsis with acute organ dysfunction
  • Sepsis with multiple organ dysfunction
  • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
  • Code first underlying infection, such as:
  • infection following a procedure (T81.4)
  • infections following infusion, transfusion and therapeutic injection (T80.2-)
  • puerperal sepsis (O85)
  • sepsis following complete or unspecified spontaneous abortion (O03.87)
  • sepsis following ectopic and molar pregnancy (O08.82)
  • sepsis following incomplete spontaneous abortion (O03.37)
  • sepsis following (induced) termination of pregnancy (O04.87)
  • sepsis NOS (A41.9)
  • Use additional code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)
Chapter Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Block General symptoms and signs (R50-R69)
Parent R65 - Symptoms and signs specifically associated with systemic inflammation and infection
ICD-10-CM Children (deeper level / typically more specific) of R65.2:
R65.20 - Severe sepsis without septic shock
R65.21 - Severe sepsis with septic shock
ICD-10-CM Siblings (same level / similar specificity) of R65.2:
R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin